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\address{Department of Physiology and Biophysics (R-430)\\
Miller School of Medicine\\
University of Miami\\
P.O. Box 016430\\
Miami, FL 33101}

\signature{Wolfgang Nonner}

\begin{letter}{Edward N. Pugh, Jr., Ph.D.\\
Editor\\The Journal of General Physiology}

\opening{Dear Dr. Pugh,}

we are submitting the revised manuscript \textbf{GP-200910211} entitled ``Ionic selectivity of L-type calcium channels by electrostatics and hard-core repulsion'', together with our response to the reviewers (revlet.pdf), and the EPS files of the revised figures (figs 1-8).

We are highly pleased by the favorable consideration that this theoretical paper has received by the Editors of JGP, and appreciate very much both the speed of the review process and the thorough evaluations given by the reviewers.

Thank you for editing our paper.

\closing{Sincerely,}

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